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Friday, May 31, 2019

Profile: Institute of Chronobiology Education & Research (June 2016 - June 2019)

Institute of Chronobiology Education & Research (ICER)  is completing 3 years next month. Though modest and low profile yet, we are committed to the chosen path of education, research and consultancy in chronobiology.

The projects undertaken by us was presented at various platforms and were appreciated as well but still we are waiting to get funding for either of our projects.

Since March 2018, Late Prin. B. V. Foundation at SP College campus is firmly associated with us and providing all the infrastructural facilities for courses, workshops and experimentation.

Here is the compiled profile of the work done so far and ongoing as well as prospective activities.

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Institute of Chronobiology Education & Research
(जैव-चक्रीय आवर्तन प्रशिक्षण आणि संशोधन संस्था)

161A, Modibaug, Ganeshkhind Road, Shivajinagar, Pune 411016
Tel No: 25519099, 8888810554     Email: duraphe@gmail.com


Chronobiology is a multidisciplinary branch of science dealing with study of biological rhythms. The free-running biological rhythms reflect the endogenous mechanisms of cyclic temporization whose expression is morphologically seen as an internal clock called body clock.

All levels of biological integration ranging from ecosystem to sub-cellular structures exhibit rhythms with diverse frequencies. Periods of most of the documented biological rhythms match with that of any one of geophysical cycles present in the nature.

Due to technology dependent round the clock work culture of humans, the entire ecosystem is facing unprecedented survival threat. Our most of the lifestyle diseases are invariably associated with altered biological clock mechanism. Hence understanding chronobiological principles and devising strategies for diagnosis and treatment of circadian dysfunction is relevant like never before.

Institute of Chronobiology Education & Research is working for popularizing the subject by providing academic courses for students and lifestyle management workshops for the professionals.


Year of inception – 2016

Type – Proprietor firm

Scope – Teaching / Research / Consultancy in Chronobiology

Affiliation – Indian Society for Chronobiology (Since March 2019)

Director – Prashant S. Duraphe, PhD

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Publications


Refereed Journals
None


Refereed Conference Proceedings

·        Ankita AS. Galinde, Aishwarya V. Bhurke, Prashant S. Duraphe (2019); Development of nasal sensors for nasal cycle characterization- Studying the ultradian biological rhythm. International Symposium on Biological Rhythms- 11th -13th March 2019, Ch. Charan Singh University, Meerut, India.

·    Ankita Galinde, Prashant S. Duraphe (2018); - Standardization of nasal cycle by temperature based nasal sensor. - World Ayurved Congress and Arogya Expo. 14th -17th December 2018, Gujarat University Convention and Exhibition Center, Ahmedabad, India.

·    Ankita Galinde, Prashant S. Duraphe (2018); Development of nasal sensors for nasal cycle characterization- Studying the ultradian body clock - World Congress on Chronomedicine- 17th -19th November 2018- King George’s Medical University, Lucknow, India.



Contributed Presentations

·     Invited talk on ‘Standardization of nasal cycle by temperature based nasal sensor’ at World Ayurved Congress and Arogya Expo, Gujarat University Convention and Exhibition Center, Ahmedabad, India 2018.

·        Invited talk on ‘Chronobiology to Chronomedicine’ at training program in Traditional medicine and Integrative health organized by Interdisciplinary School of Health Sciences, Savitribai Phule Pune University, India 2018

  
Students’ achievements at various platforms

1) Development of Nasal sensors for nasal cycle characterization (Ankita Galinde)
1st prize in oral presentation at Design Innovation Center, SPPU 2018
Best oral presentation medal at World Congress on Chronomedicine, Lucknow 2018

2) Development of thermistor based breathing sensor (Aishwarya Bhurke)
1st prize in poster presentation at IIT Powai, 2014

3) Characterization of clock gene Per1 expression in leukocytes (Bhavishya Sarma)
1st prize in poster presentation at A.Nagar College, 2014


Completed undergraduate projects

1) Study and analysis of circadian rhythms: Effect on physiological & biochemical parameters in humans
Marziyah Mahadwala (2013)

2) Development of thermistor based breathing sensor
Aishwarya Bhurke (1st prize in poster presentation at IIT Powai, 2014)

3) Characterization of clock gene Per1 expression in human leukocytes
Bhavishya Sarma (1st prize in poster presentation at A.Nagar College, 2014)

4) Characterization of clock gene Per1 expression in human hair follicles
Tanmayi Naik (2015)

5) Malignancy inducing internal time tracking genes –Literature review
Sumedha Bhosale, Shraddha Chavan (2016)

6) Autorhythmometry of Body temperature, Nasal cycle, Blood pressure, Pulse rate, Lung capacity, Sleep-wake cycle  
Ankita Galinde, Jaee Ghawali, Aditi Karanjakar, Mithilesh Gidage (2016)

7) Correlation of alcohol addiction / menstrual cycle / bipolar disorder and chronotype                   
Abhishek Kulkarni, Ankita Galinde, Nikhila Kulkarni (2016)


Completed postgraduate projects

1) Development of nasal sensors for nasal cycle characterization
Ankita Galinde (1st prize in oral presentation at Design Innovation Center, SPPU 2018, Best oral presentation medal at World Congress on Chronomedicine, Lucknow 2018, Poster presentation at International Symposium on Biological Rhythms, Meerut, 2019)

2) Correlation of chronotype with psychiatric disorders and circadian rhythm analysis by actigraphy assessment
Nikhila Kulkarni (2018)

3) Temporal expression analysis of Cryptochrome and Octopamine receptor genes in Helicoverpa armigera
Minal Ayachit (2018)


Current projects

·         Analysis of daily rhythmicity in onion peel cell size
Variation in cell size under DD/DL/LL conditions at given temperature and season.

·         Rhythmic behavior of eclosion pattern in fruit fly
Variation in eclosion pattern of Drosophila melanogaster under DD/DL/LL conditions.

·        Correlation of Chronotype and Prakriti type
Development of online questionnaires for chronotype
(https://forms.gle/DWnsE1jrJ3mKmyrT6) 
and Pakriti type (https://forms.gle/wFyuLcNdAg1oVCR17) 
to generate enough data for validation of novel concept of ChronoPrakriti.

·         Characterization of phytomelatonin from Ayurvedic formulations
Isolation and characterization of phytomelatonin from traditional sleep inducing Ayurvedic formulations.

·         Chronotyping of type 2 diabetic patients
Correlation of chronotype with known cases of diabetes mellitus.

·         Development and Calibration of thermistor based / pressure based nasal sensor
Development of nasal sensor for standardization of nasal cycle so as to establish ultradian rhythm analysis as a diagnostic tool for internal clock dysfunction.


Prospective projects

·         Circadian rhythmicity in gut, salivary and skin microbiome
·         Correlation of Chronotype / Prakriti type / Enterotype
·         Standardization of chronotype questionnaire for specific age groups / diseases
·         Standardization of nasal cycle in control population
·         Development of nasal cycle as a diagnostic tool for neurodegenerative disorders


Training courses

Certificate courses
·         Introductory course in Chronobiology
·         Basic course in Chronobiology
·         Advanced course in Chronobiology

Workshops / Seminars
·         Hands-on activities for school students
·         Seminar for School / College faculties
·         Chronotherapeutics for professionals


Elective courses designed for various life science streams

·         Animal Chronobiology
·         Plant Chronobiology
·         Microbial Chronobiology
·         Ecological Chronobiology
·         Chronobiotechnology
·         Clinical Chronobiology


Outreach activities for popularization of Chronobiology

·         Monthly Newsletter
Know Thou Biological Clock


·         Monthly open forum
Chronobiology Saturday Club


·         Monthly / Customized lifestyle management workshops
Its time to tune your ChronoPrakriti
Link for registration: https://forms.gle/b1XZpVi5cYZkHH9i6