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Saturday, August 31, 2019

KNOW THOU BIOLOGICAL CLOCK NEWSLETTER - Volume 2, Issue 6



(Saur Bhadrapad 1941 / August – September 2019) ______________________________________________________________________

Welcome to the Know Thou Biological Clock Newsletter

In this issue:

1.  What is new in this month
2.  Circadian biology of non-photosynthetic bacteria
3.  Latest trend in Chronobiology research
4.  Chronobiology in Ayurved
5.  Site of the Month
6.  Chronobiology for Students
7.  Chronobiology for Professionals
8.  ChronoPrakriti diet plan
9.  Tune your Clock – Games /
Meditation Techniques
10. Support ‘Know thou Biological Clock’ Newsletter
11. Announcements
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1. WHAT IS NEW IN THIS MONTH

Registration for ChronoPrakriti workshop is now available at following URL. We would like to request all of you to go through the link give your comments and circulate in your contacts if find suitable. (https://punefree.com/offers/chrono-prakriti). Also, the domain name is booked (www. Chronoprakriti.com) which will be linked to Bhide foundation soon. (http://bhidefoundation.org/chronobiology/)

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2.  CIRCADIAN BIOLOGY OF NON-PHOTOSYNTHETIC BACTERIA

Circadian clocks are molecular programs that impart temporal organization.  These pervasive biological systems are responsible for distinct and characteristic patterns of daily activities that are observed throughout the nature. The circadian clocks have a broad influence upon cells which can be evidenced by molecular rhythms in RNA abundance, protein modification, and metabolic pathways modification.

Although circadian clocks are seemingly ubiquitous, they have rarely been described in non-photosynthetic prokaryotes. The potential existence and nature of circadian systems in this group of organisms was reviewed by Soriano et al.

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RhythmicAlly: Your R and Shiny-Based Open-Source Ally for the Analysis of Biological Rhythms.

Research on circadian rhythms often requires researchers to estimate period, robustness/power, and phase of the rhythm. These are important to estimate, owing to the fact that they act as readouts of different features of the underlying clock. The commonly used tools, to this end, suffer from being very expensive, having very limited interactivity, being very cumbersome to use, or a combination of these. As a step toward remedying the inaccessibility to users who may not be able to afford them and to ease the analysis of biological time-series data, we have written RhythmicAlly, an open-source program using R and Shiny.

Abhilash L, Sheeba V. Chronobiology Laboratory, Neuroscience Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore, Karnataka, India.

J Biol Rhythms. 2019 Jul 16:748730419862474. doi: 10.1177/0748730419862474.
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4.  CHRONOBIOLOGY IN AYURVED – A PERSPECTIVE
Chronotype and Prakriti type has the obvious correlation. Though chronotype is validated and standardized by multiple controlled studies, Prakriti type is yet to get standardized despite having multiple online questionnaires. Central Council for Research in Ayurvedic Sciences (CCRAS), an apex organization for research in Ayurved has devised standard operating procedures for Prakriti validation.  Details can be accessed in the paper referred below.
Singh R, Ota S, Bharati, Srikanth N, Dhiman KS, Sharma L. Development of Standardized Prakriti Assessment Tool: An Overview of Ongoing CCRAS Initiatives. J Res Ayurvedic Sci 2017;1(3):165-208


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5. SITE OF THE MONTH

Indian Association for the Study of Traditional Asian Medicine, (IASTAM) India is established to develop the study of ‘Indigenous systems of Medicine’ like Ayurveda, Unani, Siddha, Yoga, Tibetan and Ethnic practices that form part of ‘Traditional Asian Medicine’ with an interdisciplinary approach. IASTAM has recognized the need to develop a distinct methodology for study and research for traditional systems of medicine. IASTAM aims to provide a platform and encourage activities for systematic positive debate & dialogue and to evolve modalities to enhance such activities across different faculties, cultures and streams of science as well as within and amongst these systems.

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6. CHRONOBIOLOGY FOR STUDENTS

Screen Time and Insomnia: What it means for Teens
For teenagers, sleep plays a critical role in staying healthy, feeling happy, maintaining good grades, and doing well in sports. But sleep doesn’t come easily for some teens. For those who struggle, it’s important to look at their electronic use.


For university students – Career in Chronobiology

The Cao Lab is interested in molecular signaling mechanisms that orchestrate daily rhythms in our brain, and how their dysregulation contributes to various neurological and psychiatric diseases with interests in the role of mammalian target of rapamycin (mTOR) signaling and mechanisms that control mRNA translation in the circadian clock.

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7. CHRONOBIOLOGY FOR PROFESSIONALS

Skipping a few meals with intermittent fasting may help people avoid cancer, diabetes, and heart disease

·         Intermittent fasting has many forms, but usually involves letting the gut rest without food for at least several hours a day.

·         People around the world have known intuitively for centuries that some sporadic intermittent fasting is good for the body.

·    Scientists now have some of the first laboratory evidence about why fasting can be beneficial: it temporarily shuts off the monocyte cells in our bodies that cause inflammation.

·         Dr. Miriam Merad, lead author of a new fasting study, said two meals a day may be ideal for human health.


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 8. CHRONOPRAKRITI DIET PLAN
Chronobiologists prescribes ‘Chronodiet’. Ayurvedic practitioners insists that the diet must be personalized based on the prakriti and season. We bring the best of both the world to you in the form of ChronoPrakriti diet.

Recipes of the month –   NA
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9. TUNE YOUR CLOCK – GAMES / MEDITATION TECHNIQUES
Like deep sleep, observing oneself also is also the best method for tuning of your clock. Unfortunately, we are so much engrossed into daily life, we forgot to take a pause and look as if we are looking into the mirror. Meditation techniques are the possible way for witnessing yourself. You may practice meditation either for spiritual experiences or for mundane physical benefits, the technique will remain the same.

ABIDE IN SOME PLACE ENDLESSLY SPACIOUS, CLEAR OF TREES, HILLS, HABITATIONS. THENCE COMES THE END OF MIND PRESSURES


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10. SUPPORT KNOW THOU BIOLOGICAL CLOCK

To ensure that this activity stays available, we need your help

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11. ANNOUNCEMENTS
·         Its time to tune your ChronoPrakriti: A daily rhythm awareness workshop for professionals – 15th September at SP college
·         Introductory Course in Chronobiology – 07th September – 29th September at Bhide foundation, SP College.
·         Certificate Course in Chronobiology – 8th August – 31st August at Garware college is postponed due to inadequate number of registrations.
Your comments and suggestions about this newsletter are always welcome.  This newsletter is always evolving — tell us what you think!
Thanks for reading!
If there are any specific topics that you would like to see here, you are most welcome to contribute and/or let me know.

Prashant S. Duraphe, PhD
(e-mail:  chronobiology2017@gmail.com)


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