(Saur Agrahayan 1941
/ November – December 2019) ______________________________________________________________________
Welcome to the Know Thou Biological Clock Newsletter
In this issue:
1. What is new in this month
2. Understanding Biological Clock
3. Latest trend in Chronobiology research
Welcome to the Know Thou Biological Clock Newsletter
In this issue:
1. What is new in this month
2. Understanding Biological Clock
3. Latest trend in Chronobiology research
4. Chronobiology and
modern medicine
5. Chronobiology and Ayurved
6. Site of the Month
7. Chronobiology for Students
8. Chronobiology for Professionals
9. ChronoPrakriti diet plan
10. Tune your Clock – Games / Meditation Techniques
5. Chronobiology and Ayurved
6. Site of the Month
7. Chronobiology for Students
8. Chronobiology for Professionals
9. ChronoPrakriti diet plan
10. Tune your Clock – Games / Meditation Techniques
11. Book review
12.
Chrono Quiz
13. Support ‘Know thou Biological Clock’ Newsletter
13. Support ‘Know thou Biological Clock’ Newsletter
14.
Announcements
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1. WHAT IS NEW IN THIS MONTH
We are trying to give wide publicity to courses initiated by
Institute of Chronobiology education and research (ICER). In that effort,
recently the website was launched. Most of the information on the site is compiled
by Ms. Ankita Galinde, a project intern at ICER. Your feedback and comments are
welcome. We will initiate online course soon through this platform. Educational
resources will be updated regularly. Do visit the site at following link. https://chronolab.wordpress.com/
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2. UNDERSTANDING
BIOLOGICAL CLOCK
Entrainment and Phase relationship of
rhythm
In
the natural world around us we mostly see rhythmic behaviours that are in tune
with environmental time cues such as sunrise/ sunset, high tide/ low tide,
high/ low temperatures. These rhythms are said to be in an “entrained state”
already. Entrainment is adjusting the internal periodicity with the period of
environmental time cue. Historically two different mechanisms- parametric and
non-parametric entrainment- were proposed by Jurgen Aschoff and Colin
Pittendrigh, respectively to explain how entrainment can be achieved.
_____________________________________________________
Rhythmicity
matters: Circadian and ultradian patterns of HPA axis activity
Oscillations are a fundamental feature
of neural and endocrine systems. The hypothalamic-pituitary-adrenal (HPA) axis
dynamically controls corticosteroid secretion in basal conditions and in
response to stress. Across the 24-h day, HPA axis activity oscillates with both
an ultradian and circadian rhythm.
https://doi.org/10.1016/j.mce.2019.110652 Available online 15 November 2019
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4. CHRONOBIOLOGY AND MODERN MEDICINE
Diet and rhythmicity in gut microbes
The
24/7 lifestyles of shift work, early morning starts, delayed bedtimes, jet lag,
and late night eating may cause circadian disruption, as our internal clocks
may fail to keep pace with the conflicting information of the external light/dark
cycle and our behaviour in an optimal way. This misalignment of the rhythms
that control our energy metabolism increases the risks of weight gain and
metabolic syndrome, including type 2 diabetes mellitus. Interestingly, an
imbalance in our intestinal microbiota is also associated with obesity and
diabetes.
____________________________________________________
5. CHRONOBIOLOGY AND
AYURVED
ChronoPrakriti
– Combined approach of non-pharmacological intervention for lifestyle diseases
faced by modern man
______________________________________________________
6. SITE OF THE MONTH
Institute of Chronobiology Education and Research (ICER) was
formally initiated at Pune, Maharashtra in June 2016 with the purpose of
chronobiology education, research and popularization.
___________________________________________________________
7. CHRONOBIOLOGY FOR STUDENTS
For school children – Melatonin
levels and usage of mobile phones
Blue light our
phones and iPads give off messes with our melatonin levels. But the effect is
even worse for kids and teenagers.
For university students – Career in Chronobiology
Cohen Laboratory at California State University, Los Angeles, USA
We seek to understand the molecular mechanisms by which the
cyanobacterial circadian clock functions in the context of the
three-dimensional cell.
___________________________________________________________
8. CHRONOBIOLOGY FOR PROFESSIONALS
Monthly rhythm of reproductive cycle in females
is extremely important as we all know. However, new research suggests that
daily, or circadian, rhythms also are important in helping to support female
health and fertility. Several new studies have shed light on this topic,
suggesting that circadian clocks in the ovary may be more important to
fertility and reproduction than previously known.
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9. CHRONOPRAKRITI
DIET PLAN
Chronobiologists prescribes ‘Chronodiet’.Ayurvedic practitioners insists that
the diet must be personalized based on the prakriti and season. We bring the
best of both the world to you in the form of ChronoPrakriti diet.
Recipes
of the month –
Vegetable
Pongal / South Indian style khichadi
______________________________________________________
10. TUNE YOUR CLOCK – GAMES / MEDITATION TECHNIQUES
Like
deep sleep, observing oneself is also the best method for tuning of your clock.
Unfortunately, we are so much engrossed into daily life, we forgot to take a
pause and look as if we are looking into the mirror. Meditation techniques are
the possible way for witnessing yourself. You may practice meditation either
for spiritual experiences or for mundane physical benefits, the technique will
remain the same.
WITH YOUR
ENTIRE CONSCIOUSNESS IN THE VERY START OF DESIRE, OF KNOWING, KNOW
_____________________________________________________________________
11. BOOK
REVIEW
Circadian Rhythms: Methods &
Protocols
Ezio Rosato ED. Humana Press, Totowa,
New Jersey 2007, ISBN 978-1-58829-417-3
The aim of Circadian Rhythms: Methods
and Protocols has been to provide a resource that can be adopted by several
types of users such as seasoned chronobiologist to a novice to the field. This
task has been achieved by collecting a full range of methods, many provided by
leading experts in the field, that should satisfy the needs of the audience of
varied background, by illustrating procedures that have been recently
introduced in circadian studies, and by presenting, for many basic techniques,
variations to take into account the peculiarities of different model systems.
_________________________________________________________
12. CHRONO
QUIZ
Match the
following
|
1) 2017 Nobel prize in
chronobiology
|
a) Jagadishchandra Basu
|
|
2) Father of classical
chronobiology
|
b) Ronald Konopka
|
|
3) Identification of first clock
gene
|
c) Colin Pittendrigh, Juergen
Aschoff
|
|
4) First scientific observation
& documentation of rhythmicity
|
d) J. Hall, M. Rosbash, M. Young
|
|
5) Father of Indian chronobiology
|
e) Jacques d’Ortous de Mairan
|
Answer
will be given in the next newsletter!
________________________________________________
13.
SUPPORT KNOW THOU BIOLOGICAL CLOCK
To ensure that this activity stays available, we need your help
To ensure that this activity stays available, we need your help
____________
14. ANNOUNCEMENTS
·
It’s time to tune your ChronoPrakriti: A daily rhythm
awareness workshop for professionals and
students – Tentatively in first week of December at Bhide Foundation
·
Introductory
Course in Chronobiology – Starts
first Saturday of each month at Bhide Foundation, SP
College.
·
Basic
Course in Chronobiology – Starts in August & December of each year at Abasaheb
Garware college
https://docs.google.com/document/d/1VE48mYDMd3nZBNXTIkrR_kjPziY5mUt8q0MO5NlxcSQ/edit?usp=sharing
_________________________________________________________
_________________________________________________________
Your comments and suggestions about this newsletter are
always welcome. This
newsletter is always evolving - tell us what you think!
Thanks
for reading! If there
are any specific topics that you
would like to see here, you are most welcome to contribute and/or let me know.
Prashant S. Duraphe, PhD
e-mail: chronobiology2017@gmail.com
Prashant S. Duraphe, PhD
e-mail: chronobiology2017@gmail.com
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